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Target
Sialidase-2
Ligand
BDBM50468556
Substrate
n/a
Meas. Tech.
ChEMBL_1799822 (CHEMBL4272114)
IC50
>500000±n/a nM
Citation
 Richards, MR; Guo, T; Hunter, CD; Cairo, CW Molecular dynamics simulations of viral neuraminidase inhibitors with the human neuraminidase enzymes: Insights into isoenzyme selectivity. Bioorg Med Chem 26:5349-5358 (2018) [PubMed]  Article 
Target
Name:
Sialidase-2
Synonyms:
Cytosolic sialidase | N-acetyl-alpha-neuraminidase 2 | NEU2 | NEUR2_HUMAN | Sialidase 2 | Sialidase-2
Type:
PROTEIN
Mol. Mass.:
42256.20
Organism:
Homo sapiens (Human)
Description:
ChEMBL_960638
Residue:
380
Sequence:
MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLQTRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLHDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVETGEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSGPGSPAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEYLPQ
  
Inhibitor
Name:
BDBM50468556
Synonyms:
CHEMBL4280954
Type:
Small organic molecule
Emp. Form.:
C11H19NO9
Mol. Mass.:
309.2699
SMILES:
[H][C@]1(OC(O)(C[C@H](O)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)CO |r|
Structure:
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