Reaction Details Report a problem with these data
Target
Protease
Ligand
BDBM50469407
Substrate
n/a
Meas. Tech.
ChEMBL_1804115 (CHEMBL4276407)
Ki
0.016000±n/a nM
Citation
Ghosh, AK; Williams, JN; Ho, RY; Simpson, HM; Hattori, SI; Hayashi, H; Agniswamy, J; Wang, YF; Weber, IT; Mitsuya, H Design and Synthesis of Potent HIV-1 Protease Inhibitors Containing Bicyclic Oxazolidinone Scaffold as the P2 Ligands: Structure-Activity Studies and Biological and X-ray Structural Studies. J Med Chem 61:9722-9737 (2018) [PubMed] Article
More Info.:
Target
Name:
Protease
Synonyms:
n/a
Type:
Enzyme
Mol. Mass.:
10904.79
Organism:
Human immunodeficiency virus 1 (HIV-1)
Description:
Q9YQ12
Residue:
99
Sequence:
PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF