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Target
Choline O-acetyltransferase
Ligand
BDBM50026475
Substrate
n/a
Meas. Tech.
ChEBML_27376
Ki
6400000±n/a nM
Citation
 Cohen, SG; Chishti, SB; Elkind, JL; Reese, H; Cohen, JB Effects of charge, volume, and surface on binding of inhibitor and substrate moieties to acetylcholinesterase. J Med Chem 28:1309-13 (1985) [PubMed]  Article 
Target
Name:
Choline O-acetyltransferase
Synonyms:
CLAT_RAT | Chat | Choline Acetyltransferase | Choline O-acetyltransferase | Choline acetylase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
71875.58
Organism:
RAT
Description:
Choline Acetyltransferase 0 RAT::P32738
Residue:
640
Sequence:
MPILEKAPQKMPVKASSWEELDLPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAIVKRFGAPGGLGETLQEKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFQDTNDQLRFAACLISGVLSYKTLLDSHSLPTDWAKGQLSGQPLCMKQYYRLFSSYRLPGHTQDTLVAQKSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAKARTVLLKDSTNRDSLDMIERCICLVCLDGPGTGELSDTHRALQLLHGGGCSLNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMMTSNKKLVRADSVSELPAPRRLRLKCSPETQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKYSPDGFIQVALQLAYYRLYQRLVPTYESASIRRFQEGRVDNIRSATPEALAFVQAMTDHKAAMPASEKLQLLQTAMQAHKQYTVMAITGMAIDNHLLALRELARDLCKEPPEMFMDETYLMSNRFVLSTSQVPTTMEMFCCYGPVVPNGNGACYNPQPEAITFCISSFHSCKETSSVEFAEAVGASLVDMRDLCSSRQPADSKPPAPKEKARGPSQAKQS
  
Inhibitor
Name:
BDBM50026475
Synonyms:
Acetic acid 2-methanesulfonyl-ethyl ester | CHEMBL25617
Type:
Small organic molecule
Emp. Form.:
C5H10O4S
Mol. Mass.:
166.196
SMILES:
CC(=O)OCCS(C)(=O)=O
Structure:
Search PDB for entries with ligand similarity: