Reaction Details Report a problem with these data
Target
Melatonin receptor type 1C
Ligand
BDBM50470174
Substrate
n/a
Meas. Tech.
ChEMBL_104757 (CHEMBL712440)
Ki
0.540000±n/a nM
Citation
 Langlois, M; Brémont, B; Shen, S; Poncet, A; Andrieux, J; Sicsic, S; Serraz, I; Mathé-Allainmat, M; Renard, P; Delagrange, P Design and synthesis of new naphthalenic derivatives as ligands for 2-[125I]iodomelatonin binding sites. J Med Chem 38:2050-60 (1995) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1C
Synonyms:
CKB | MTR1C_CHICK | Mel-1C-R | Mel1c receptor | Melatonin receptor type 1C
Type:
PROTEIN
Mol. Mass.:
38595.98
Organism:
Gallus gallus
Description:
ChEMBL_104739
Residue:
346
Sequence:
MERPGSNGSCSGCRLEGGPAARAASGLAAVLIVTIVVDVLGNALVILSVLRNKKLRNAGNIFVVSLSVADLVVAVYPYPLILSAIFHNGWTMGNIHCQISGFLMGLSVIGSIFNITAIAINRYCYICHSLRYDKLFNLKNTCCYICLTWTLTVVAIVPNFFVGSLQYDPRIYSCTFAQTVSTSYTITVVVVHFIVPLSIVTFCYLRIWILVIQVKHRVRQDCKQKIRAADIRNFLTMFVVFVLFAVCWGPLNFIGLAVSINPSKVQPHIPEWLFVLSYFMAYFNSCLNAVIYGLLNQNFRKEYKRILLMLRTPRLLFIDVSKGGTEGLKSKPSPAVTNNNQAEIHL
  
Inhibitor
Name:
BDBM50470174
Synonyms:
CHEMBL62992
Type:
Small organic molecule
Emp. Form.:
C15H14F3NO2
Mol. Mass.:
297.2724
SMILES:
COc1ccc2ccccc2c1CCNC(=O)C(F)(F)F
Structure:
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