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Target
Beta-casein
Ligand
BDBM21397
Substrate
n/a
Meas. Tech.
ChEMBL_32296 (CHEMBL646243)
Ki
1.5±n/a nM
Citation
 Giardinà, D; Crucianelli, M; Romanelli, R; Leonardi, A; Poggesi, E; Melchiorre, C Synthesis and biological profile of the enantiomers of [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-cis-octahydroquinoxalin- 1-yl]furan-2-ylmethanone (cyclazosin), a potent competitive alpha 1B- adrenoceptor antagonist. J Med Chem 39:4602-7 (1996) [PubMed]  Article 
Target
Name:
Beta-casein
Synonyms:
Beta-casein | CASB_RAT | Csn2 | Csnb
Type:
PROTEIN
Mol. Mass.:
25368.99
Organism:
Rattus norvegicus
Description:
ChEMBL_12483
Residue:
231
Sequence:
MKVFILACLVALALAREKDAFTVSSETGSISSEESVEHINEKLQKVKLMGQVQSEDVLQNKFHSGIQSEPQAIPYAQTISCSPIPQNIQPIAQPPVVPTVGPIISPELESFLKAKATVLPKHKQMPFLNSETVLRLFNSQIPSLDLANLHLPQSPAQLQAQIVQAFPQTPAVVSSQPQLSHPQSKSQYLVQQLAPLFQQGMPVQDLLQYLDLLLNPTLQFLATQQLHSTSV
  
Inhibitor
Name:
BDBM21397
Synonyms:
8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one | 8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one | 8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one | CHEMBL267930 | MLS000028615 | SMR000058674 | SPIPERONE | Spiroperidol | US9359372, Spiperone | [3H]-Spiroperidol | cid_5265
Type:
radiolabeled ligand
Emp. Form.:
C23H26FN3O2
Mol. Mass.:
395.4698
SMILES:
Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: