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Target
Beta-casein
Ligand
BDBM50274049
Substrate
n/a
Meas. Tech.
ChEMBL_32297 (CHEMBL646244)
Ki
0.208930±n/a nM
Citation
 Giardinà, D; Crucianelli, M; Romanelli, R; Leonardi, A; Poggesi, E; Melchiorre, C Synthesis and biological profile of the enantiomers of [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-cis-octahydroquinoxalin- 1-yl]furan-2-ylmethanone (cyclazosin), a potent competitive alpha 1B- adrenoceptor antagonist. J Med Chem 39:4602-7 (1996) [PubMed]  Article 
Target
Name:
Beta-casein
Synonyms:
Beta-casein | CASB_RAT | Csn2 | Csnb
Type:
PROTEIN
Mol. Mass.:
25368.99
Organism:
Rattus norvegicus
Description:
ChEMBL_12483
Residue:
231
Sequence:
MKVFILACLVALALAREKDAFTVSSETGSISSEESVEHINEKLQKVKLMGQVQSEDVLQNKFHSGIQSEPQAIPYAQTISCSPIPQNIQPIAQPPVVPTVGPIISPELESFLKAKATVLPKHKQMPFLNSETVLRLFNSQIPSLDLANLHLPQSPAQLQAQIVQAFPQTPAVVSSQPQLSHPQSKSQYLVQQLAPLFQQGMPVQDLLQYLDLLLNPTLQFLATQQLHSTSV
  
Inhibitor
Name:
BDBM50274049
Synonyms:
CHEMBL342062
Type:
Small organic molecule
Emp. Form.:
C23H27N5O4
Mol. Mass.:
437.4916
SMILES:
[H][C@@]12CCCC[C@]1([H])N(CCN2C(=O)c1ccco1)c1nc(N)c2cc(OC)c(OC)cc2n1
Structure:
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