Reaction Details Report a problem with these data
Target
Melatonin receptor type 1C
Ligand
BDBM50470174
Substrate
n/a
Meas. Tech.
ChEMBL_104764 (CHEMBL714909)
Ki
0.549541±n/a nM
Citation
 Sicsic, S; Serraz, I; Andrieux, J; Brémont, B; Mathé-Allainmat, M; Poncet, A; Shen, S; Langlois, M Three-dimensional quantitative structure-activity relationship of melatonin receptor ligands: a comparative molecular field analysis study. J Med Chem 40:739-48 (1997) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1C
Synonyms:
CKB | MTR1C_CHICK | Mel-1C-R | Mel1c receptor | Melatonin receptor type 1C
Type:
PROTEIN
Mol. Mass.:
38595.98
Organism:
Gallus gallus
Description:
ChEMBL_104739
Residue:
346
Sequence:
MERPGSNGSCSGCRLEGGPAARAASGLAAVLIVTIVVDVLGNALVILSVLRNKKLRNAGNIFVVSLSVADLVVAVYPYPLILSAIFHNGWTMGNIHCQISGFLMGLSVIGSIFNITAIAINRYCYICHSLRYDKLFNLKNTCCYICLTWTLTVVAIVPNFFVGSLQYDPRIYSCTFAQTVSTSYTITVVVVHFIVPLSIVTFCYLRIWILVIQVKHRVRQDCKQKIRAADIRNFLTMFVVFVLFAVCWGPLNFIGLAVSINPSKVQPHIPEWLFVLSYFMAYFNSCLNAVIYGLLNQNFRKEYKRILLMLRTPRLLFIDVSKGGTEGLKSKPSPAVTNNNQAEIHL
  
Inhibitor
Name:
BDBM50470174
Synonyms:
CHEMBL62992
Type:
Small organic molecule
Emp. Form.:
C15H14F3NO2
Mol. Mass.:
297.2724
SMILES:
COc1ccc2ccccc2c1CCNC(=O)C(F)(F)F
Structure:
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