Reaction Details Report a problem with these data
Target
Melatonin receptor type 1C
Ligand
BDBM50471024
Substrate
n/a
Meas. Tech.
ChEMBL_104616 (CHEMBL715564)
Ki
0.970000±n/a nM
Citation
 Davies, DJ; Garratt, PJ; Tocher, DA; Vonhoff, S; Davies, J; Teh, MT; Sugden, D Mapping the melatonin receptor. 5. Melatonin agonists and antagonists derived from tetrahydrocyclopent[b]indoles, tetrahydrocarbazoles and hexahydrocyclohept[b]indoles. J Med Chem 41:451-67 (1998) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1C
Synonyms:
CKB | MTR1C_CHICK | Mel-1C-R | Mel1c receptor | Melatonin receptor type 1C
Type:
PROTEIN
Mol. Mass.:
38595.98
Organism:
Gallus gallus
Description:
ChEMBL_104739
Residue:
346
Sequence:
MERPGSNGSCSGCRLEGGPAARAASGLAAVLIVTIVVDVLGNALVILSVLRNKKLRNAGNIFVVSLSVADLVVAVYPYPLILSAIFHNGWTMGNIHCQISGFLMGLSVIGSIFNITAIAINRYCYICHSLRYDKLFNLKNTCCYICLTWTLTVVAIVPNFFVGSLQYDPRIYSCTFAQTVSTSYTITVVVVHFIVPLSIVTFCYLRIWILVIQVKHRVRQDCKQKIRAADIRNFLTMFVVFVLFAVCWGPLNFIGLAVSINPSKVQPHIPEWLFVLSYFMAYFNSCLNAVIYGLLNQNFRKEYKRILLMLRTPRLLFIDVSKGGTEGLKSKPSPAVTNNNQAEIHL
  
Inhibitor
Name:
BDBM50471024
Synonyms:
CHEMBL53824
Type:
Small organic molecule
Emp. Form.:
C17H22N2O2
Mol. Mass.:
286.3688
SMILES:
COc1ccc2n(C)c3CCCC(CNC(C)=O)c3c2c1
Structure:
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