Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50472721
Substrate
n/a
Meas. Tech.
ChEMBL_46468 (CHEMBL858761)
Ki
20±n/a nM
Citation
 Fichera, M; Cruciani, G; Bianchi, A; Musumarra, G A 3D-QSAR study on the structural requirements for binding to CB(1) and CB(2) cannabinoid receptors. J Med Chem 43:2300-9 (2000) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50472721
Synonyms:
5''-F3-delta8-THC | CHEMBL74662
Type:
Small organic molecule
Emp. Form.:
C21H27F3O2
Mol. Mass.:
368.4331
SMILES:
CC1=CCC2C(C1)c1c(O)cc(CCCCC(F)(F)F)cc1OC2(C)C |t:1|
Structure:
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