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Target
Cholecystokinin receptor type A
Ligand
BDBM50472861
Substrate
n/a
Meas. Tech.
ChEMBL_47661 (CHEMBL657373)
Ki
48±n/a nM
Citation
 Ursini, A; Capelli, AM; Carr, RA; Cassarà, P; Corsi, M; Curcuruto, O; Curotto, G; Dal Cin, M; Davalli, S; Donati, D; Feriani, A; Finch, H; Finizia, G; Gaviraghi, G; Marien, M; Pentassuglia, G; Polinelli, S; Ratti, E; Reggiani, AM; Tarzia, G; Tedesco, G; Tranquillini, ME; Trist, DG; Van Amsterdam, FT; Reggiani, A Synthesis and SAR of new 5-phenyl-3-ureido-1,5-benzodiazepines as cholecystokinin-B receptor antagonists. J Med Chem 43:3596-613 (2000) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50472861
Synonyms:
CHEMBL121267
Type:
Small organic molecule
Emp. Form.:
C29H27ClN4O3
Mol. Mass.:
515.003
SMILES:
Clc1cccc(NC(=O)NC2C(=O)N(C3CC4CCC3C4)c3ccccc3N(c3ccccc3)C2=O)c1 |TLB:13:14:20:18.17|
Structure:
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