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Target
Carbonic anhydrase 4
Ligand
BDBM10860
Substrate
n/a
Meas. Tech.
ChEMBL_344236 (CHEMBL867755)
Ki
2790±n/a nM
Citation
 Agrawal, VK; Singh, J; Khadikar, PV; Supuran, CT QSAR study on topically acting sulfonamides incorporating GABA moieties: a molecular connectivity approach. Bioorg Med Chem Lett 16:2044-51 (2006) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 4
Synonyms:
CA-IV | CA4 | CAH4_BOVIN | Carbonate dehydratase IV | Carbonic Anhydrase IV | Carbonic anhydrase | Carbonic anhydrase 4
Type:
Enzyme
Mol. Mass.:
35152.74
Organism:
Bos taurus (bovine)
Description:
Bovine isozyme, isolated from lung microsomes
Residue:
312
Sequence:
MRLLLALLVLAAAPPQARAASHWCYQIQVKPSNYTCLEPDEWEGSCQNNRQSPVNIVTAKTQLDPNLGRFSFSGYNMKHQWVVQNNGHTVMVLLENKPSIAGGGLSTRYQATQLHLHWSRAMDRGSEHSFDGERFAMEMHIVHEKEKGLSGNASQNQFAEDEIAVLAFMVEDGSKNVNFQPLVEALSDIPRPNMNTTMKEGVSLFDLLPEEESLRHYFRYLGSLTTPTCDEKVVWTVFQKPIQLHRDQILAFSQKLFYDDQQKVNMTDNVRPVQSLGQRQVFRSGAPGLLLAQPLPTLLAPVLACLTVGFLR
  
Inhibitor
Name:
BDBM10860
Synonyms:
4-(aminomethyl)benzene-1-sulfonamide | CHEMBL419 | MAFENIDE | aromatic sulfonamide compound 6 | aromatic/heteroaromatic sulfonamide 5 | hCA inhibitor, 9
Type:
Small organic molecule
Emp. Form.:
C7H10N2O2S
Mol. Mass.:
186.232
SMILES:
NCc1ccc(cc1)S(N)(=O)=O
Structure:
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