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Target
D(2) dopamine receptor
Ligand
BDBM50476121
Substrate
n/a
Meas. Tech.
ChEMBL_426001 (CHEMBL907460)
Ki
3.1±n/a nM
Citation
 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Towards a new generation of potential antipsychotic agents combining D2 and 5-HT1A receptor activities. J Med Chem 50:865-76 (2007) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50476121
Synonyms:
CHEMBL221957
Type:
Small organic molecule
Emp. Form.:
C25H33NO2
Mol. Mass.:
379.535
SMILES:
CC(C)Oc1ccccc1OCCNCc1cccc(c1)C1=CCCCCC1 |t:23|
Structure:
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