Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50477817
Substrate
n/a
Meas. Tech.
ChEMBL_459967 (CHEMBL943095)
Ki
<10000±n/a nM
Citation
 Woods, CR; Hack, MD; Allison, BD; Phuong, VK; Rosen, MD; Morton, MF; Prendergast, CE; Barrett, TD; Shankley, NP; Rabinowitz, MH Synthesis and solid-phase purification of anthranilic sulfonamides as CCK-2 ligands. Bioorg Med Chem Lett 17:6905-9 (2007) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_HUMAN | CCKRA | Cholecystokinin receptor | Cholecystokinin receptor type A | Cholecystokinin-1 Receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
47859.34
Organism:
Homo sapiens (Human)
Description:
Stable expression of human CCK-1 receptors in HEK 293 cells.
Residue:
428
Sequence:
MDVVDSLLVNGSNITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGARGEVGEEEEGGTTGASLSRFSYSHMSASVPPQ
  
Inhibitor
Name:
BDBM50477817
Synonyms:
CHEMBL387285
Type:
Small organic molecule
Emp. Form.:
C18H17ClN4O3S2
Mol. Mass.:
436.936
SMILES:
Clc1ccc(NS(=O)(=O)c2cccc3nsnc23)c(c1)C(=O)N1CCCCC1
Structure:
Search PDB for entries with ligand similarity: