Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM50000407
Substrate
n/a
Meas. Tech.
ChEMBL_471648 (CHEMBL933892)
Ki
76000±n/a nM
Citation
 Horsfall, LE; Garau, G; Liénard, BM; Dideberg, O; Schofield, CJ; Frère, JM; Galleni, M Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila. Antimicrob Agents Chemother 51:2136-42 (2007) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
3.5.2.6 | Beta-lactamase | cphA2
Type:
PROTEIN
Mol. Mass.:
28064.62
Organism:
Aeromonas hydrophila
Description:
ChEMBL_117200
Residue:
254
Sequence:
MMKGWMKCGLAGAVVLMASFWGGSVRAAGMSLTQVSGPVYVVEDNYYVQENSMVYFGAKGVTVVGATWTPDTARELHKLIKRVSRQPVLEVINTNYHTDRAGGNAYWKSIGAKVVSTRQTRDLMKSDWAEIVAFTRKGLPEYPDLPLVLPNVVHEGDFTLQEGKLRAFYAGPAHTPDGIFVYFPDQQVLYGNCILKEKLGNLSFADVKAYPRTLERLKAMKLPIKTVVGGHDSPLHGPELIDHYEALIKAAPQS
  
Inhibitor
Name:
BDBM50000407
Synonyms:
2-carboxypyridine | CHEMBL72628 | alpha-picolinic acid | alpha-pyridinecarboxylic acid | o-pyridinecarboxylic acid | picolinic acid | pyridine-2-carboxylic acid
Type:
Small organic molecule
Emp. Form.:
C6H5NO2
Mol. Mass.:
123.1094
SMILES:
OC(=O)c1ccccn1
Structure:
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