Reaction Details Report a problem with these data
Target
Hydroxyacylglutathione hydrolase, mitochondrial
Ligand
BDBM50028202
Substrate
n/a
Meas. Tech.
ChEBML_71301
Ki
65000±n/a nM
Citation
 Hsu, YR; Norton, SJ S-carbobenzoxyglutathione: a competitive inhibitor of mammalian glyoxalase II. J Med Chem 26:1784-5 (1984) [PubMed]  Article 
Target
Name:
Hydroxyacylglutathione hydrolase, mitochondrial
Synonyms:
GLO2_RAT | Glyoxalase II | Hagh | Rsp29
Type:
PROTEIN
Mol. Mass.:
34116.42
Organism:
Rattus norvegicus
Description:
ChEMBL_71301
Residue:
309
Sequence:
MVLGRGSLCLRSLSVLGAACARRGLGQALLGLSLCHTDFRKNLTVQQDMMKIELLPALTDNYMYLIIDEDTQEAAVVDPVQPQKVIETVKKHRVKLTTVLTTHHHWDHAGGNEKLVKLEPGLKVYGGDDRIGALTHKVTHLSTLEVGSLSVKCLSTPCHTSGHICYFVSKPGSSEPSAVFTGDTLFVAGCGKFYEGTADEMYKALLEVLGRLPPDTKVICGHEYTVNNLKFARHVEPGNTAVQEKLAWAKEKNAIGEPTVPSTLAEEFTYNPFMRVKEKTVQQHAGETDPVTTMRAIRREKDQFKVPRD
  
Inhibitor
Name:
BDBM50028202
Synonyms:
(S)-2-Amino-4-[(R)-2-benzyloxycarbonylsulfanyl-1-(carboxymethyl-carbamoyl)-ethylcarbamoyl]-butyric acid | CHEMBL50249
Type:
Small organic molecule
Emp. Form.:
C18H23N3O8S
Mol. Mass.:
441.456
SMILES:
N[C@@H](CCC(=O)N[C@@H](CSC(=O)OCc1ccccc1)C(=O)NCC(O)=O)C(O)=O
Structure:
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