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Target
Glutamate transporter homolog
Ligand
BDBM50247191
Substrate
n/a
Meas. Tech.
ChEMBL_476894 (CHEMBL940158)
Kd
100±n/a nM
Citation
 Boudker, O; Ryan, RM; Yernool, D; Shimamoto, K; Gouaux, E Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter. Nature 445:387-93 (2007) [PubMed]  Article 
Target
Name:
Glutamate transporter homolog
Synonyms:
GLT_PYRHO | Glt(Ph) | Glutamate transporter homolog | Sodium-aspartate symporter Glt(Ph) | Sodium-dependent aspartate transporter
Type:
PROTEIN
Mol. Mass.:
44812.64
Organism:
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 /NBRC 100139 / OT-3)
Description:
ChEMBL_118422
Residue:
425
Sequence:
MGLYRKYIEYPVLQKILIGLILGAIVGLILGHYGYADAVKTYVKPFGDLFVRLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPKQAPPLVKILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVKVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKKAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVCTFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLAMVLESVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTEGELEKGVIA
  
Inhibitor
Name:
BDBM50247191
Synonyms:
(2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL475341 | D,L-threo-beta-benzyloxyaspartate | DL-2-amino-3-(benzyloxy)succinic acid | DL-threo-beta-benzyloxyaspartate
Type:
Small organic molecule
Emp. Form.:
C11H13NO5
Mol. Mass.:
239.2246
SMILES:
NC(C(OCc1ccccc1)C(O)=O)C(O)=O
Structure:
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