Target
Type-1 angiotensin II receptor A
Ligand
BDBM50149609
Substrate
n/a
Meas. Tech.
ChEMBL_510120 (CHEMBL998774)
IC50
197000±n/a nM
Citation
 Ohno, OYe, MKoyama, TYazawa, KMura, EMatsumoto, HIchino, TYamada, KNakamura, KOhno, TYamaguchi, KIshida, JFukamizu, AUemura, D Inhibitory effects of benzyl benzoate and its derivatives on angiotensin II-induced hypertension. Bioorg Med Chem 16:7843-52 (2008) [PubMed]  Article 
Target
Name:
Type-1 angiotensin II receptor A
Synonyms:
AGTRA_MOUSE | AT1A | Agtr1 | Agtr1a | Angiotensin II type-1A receptor | Type-1A angiotensin II receptor
Type:
PROTEIN
Mol. Mass.:
40876.47
Organism:
Mus musculus
Description:
ChEMBL_101531
Residue:
359
Sequence:
MALNSSTEDGIKRIQDDCPRAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVCAFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSAAKKPASCSEVE
  
Inhibitor
Name:
BDBM50149609
Synonyms:
(E)-3-Phenyl-acrylic acid benzyl ester | CHEMBL361197 | benzyl (E)-cinnamate | benzyl cinnamate | benzyltrans cinnamate
Type:
Small organic molecule
Emp. Form.:
C16H14O2
Mol. Mass.:
238.2812
SMILES:
O=C(OCc1ccccc1)\C=C\c1ccccc1
Structure:
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