Reaction Details Report a problem with these data
Target
Reverse transcriptase
Ligand
BDBM50478439
Substrate
n/a
Meas. Tech.
ChEMBL_549454 (CHEMBL996388)
IC50
>100000±n/a nM
Citation
 Loya, S; Reshef, V; Mizrachi, E; Silberstein, C; Rachamim, Y; Carmeli, S; Hizi, A The inhibition of the reverse transcriptase of HIV-1 by the natural sulfoglycolipids from cyanobacteria: contribution of different moieties to their high potency. J Nat Prod 61:891-5 (1998) [PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50478439
Synonyms:
CHEBI:63774 | CHEMBL443117
Type:
Small organic molecule
Emp. Form.:
C41H78O10
Mol. Mass.:
731.052
SMILES:
CCCCCCCCCCCCCCCC(=O)OC[C@H](CO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)OC(=O)CCCCCCCCCCCCCCC |r|
Structure:
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