Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM50478547
Substrate
n/a
Meas. Tech.
ChEMBL_507646 (CHEMBL948647)
IC50
230±n/a nM
Citation
 Potts, BC; Faulkner, DJ; Jacobs, RS Phospholipase A2 inhibitors from marine organisms. J Nat Prod 55:1701-17 (1992) [PubMed]  Article 
Target
Name:
Phospholipase A2
Synonyms:
Allergen Api m I | Allergen=Api m 1 | PA2_APIME | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2 (Bee)
Type:
PROTEIN
Mol. Mass.:
19061.47
Organism:
Apis mellifera
Description:
ChEMBL_1277435
Residue:
167
Sequence:
MQVVLGSLFLLLLSTSHGWQIRDRIGDNELEERIIYPGTLWCGHGNKSSGPNELGRFKHTDACCRTHDMCPDVMSAGESKHGLTNTASHTRLSCDCDDKFYDCLKNSADTISSYFVGKMYFNLIDTKCYKLEHPVTGCGERTEGRCLHYTVDKSKPKVYQWFDLRKY
  
Inhibitor
Name:
BDBM50478547
Synonyms:
Luffariellolide
Type:
Small organic molecule
Emp. Form.:
C25H38O3
Mol. Mass.:
386.5674
SMILES:
C\C(CC\C=C(/C)CCC1=C(C)CCCC1(C)C)=C/CCC1=CC(=O)OC1O |c:9,t:22|
Structure:
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