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Target
Stromelysin-3
Ligand
BDBM50480363
Substrate
n/a
Meas. Tech.
ChEMBL_501124 (CHEMBL978902)
IC50
0.025±n/a nM
Citation
 Galal, SA; Abd El-All, AS; Abdallah, MM; El-Diwani, HI Synthesis of potent antitumor and antiviral benzofuran derivatives. Bioorg Med Chem Lett 19:2420-8 (2009) [PubMed]  Article 
Target
Name:
Stromelysin-3
Synonyms:
MMP11_MOUSE | Matrix metalloproteinase 11 | Mmp11
Type:
PROTEIN
Mol. Mass.:
55452.62
Organism:
Mus musculus
Description:
ChEMBL_106453
Residue:
492
Sequence:
MARAACLLRAISRVLLLPLPLLLLLLLLLPSPLMARARPPESHRHHPVKKGPRLLHAALPNTLTSVPASHWVPSPAGSSRPLRCGVPDLPDVLNARNRQKRFVLSGGRWEKTDLTYRILRFPWQLVREQVRQTVAEALQVWSEVTPLTFTEVHEGRADIMIDFARYWHGDNLPFDGPGGILAHAFFPKTHREGDVHFDYDETWTIGDNQGTDLLQVAAHEFGHVLGLQHTTAAKALMSPFYTFRYPLSLSPDDRRGIQHLYGRPQMAPTSPAPTLSSQAGTDTNEIALLEPETPPDVCETSFDAVSTIRGELFFFKAGFVWRLRSGRLQPGYPALASRHWQGLPSPVDAAFEDAQGQIWFFQGAQYWVYDGEKPVLGPAPLSKLGLQGSPVHAALVWGPEKNKIYFFRGGDYWRFHPRTQRVDNPVPRRSTDWRGVPSEIDAAFQDAEGYAYFLRGHLYWKFDPVKVKVLEGFPRPVGPDFFDCAEPANTFR
  
Inhibitor
Name:
BDBM50480363
Synonyms:
CHEMBL449897
Type:
Small organic molecule
Emp. Form.:
C18H16N2O5
Mol. Mass.:
340.33
SMILES:
COc1c(O)c(C(=O)\C=C\Nc2ccncc2)c(OC)c2ccoc12
Structure:
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