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Target
Reverse transcriptase
Ligand
BDBM50480364
Substrate
n/a
Meas. Tech.
ChEMBL_501126 (CHEMBL978904)
IC50
17530±n/a nM
Citation
 Galal, SA; Abd El-All, AS; Abdallah, MM; El-Diwani, HI Synthesis of potent antitumor and antiviral benzofuran derivatives. Bioorg Med Chem Lett 19:2420-8 (2009) [PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50480364
Synonyms:
CHEMBL468539
Type:
Small organic molecule
Emp. Form.:
C14H10O6
Mol. Mass.:
274.2256
SMILES:
COc1c2occc2c(OC)c2c1occ(C=O)c2=O
Structure:
Search PDB for entries with ligand similarity: