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Target
Reverse transcriptase
Ligand
BDBM50480367
Substrate
n/a
Meas. Tech.
ChEMBL_501126 (CHEMBL978904)
IC50
9440±n/a nM
Citation
 Galal, SA; Abd El-All, AS; Abdallah, MM; El-Diwani, HI Synthesis of potent antitumor and antiviral benzofuran derivatives. Bioorg Med Chem Lett 19:2420-8 (2009) [PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50480367
Synonyms:
CHEMBL468747
Type:
Small organic molecule
Emp. Form.:
C22H17N3O5
Mol. Mass.:
403.3875
SMILES:
COc1c(O)c(C(=O)C2=CN3C(Nc4ccccc34)=CN=C2)c(OC)c2ccoc12 |c:20,22,t:8|
Structure:
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