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Target
Choline/ethanolaminephosphotransferase 1
Ligand
BDBM50309658
Substrate
n/a
Meas. Tech.
ChEMBL_606314 (CHEMBL1070006)
IC50
28±n/a nM
Citation
 Smith, CJ; Ali, A; Chen, L; Hammond, ML; Anderson, MS; Chen, Y; Eveland, SS; Guo, Q; Hyland, SA; Milot, DP; Sparrow, CP; Wright, SD; Sinclair, PJ 2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety. Bioorg Med Chem Lett 20:346-9 (2010) [PubMed]  Article 
Target
Name:
Choline/ethanolaminephosphotransferase 1
Synonyms:
2.7.8.1 | 2.7.8.2 | CEPT1 | CEPT1_HUMAN | Choline/ethanolaminephosphotransferase 1 | hCEPT1
Type:
PROTEIN
Mol. Mass.:
46568.68
Organism:
Homo sapiens
Description:
ChEMBL_117345
Residue:
416
Sequence:
MSGHRSTRKRCGDSHPESPVGFGHMSTTGCVLNKLFQLPTPPLSRHQLKRLEEHRYQSAGRSLLEPLMQGYWEWLVRRVPSWIAPNLITIIGLSINICTTILLVFYCPTATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLGTNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIIDVTEVQIFIIIMHLLAVIGGPPFWQSMIPVLNIQMKIFPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTIAGTSVLSPFLHIGSVITLAAMIYKKSAVQLFEKHPCLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFIDEYIVLWIALVFSFFDLIRYCVSVCNQIASHLHIHVFRIKVSTAHSNHH
  
Inhibitor
Name:
BDBM50309658
Synonyms:
CHEMBL593709 | N-(4-(5-cyano-7-(2-hydroxypropan-2-yl)benzo[d]oxazol-2-yl)phenyl)-2-(o-tolyloxy)acetamide
Type:
Small organic molecule
Emp. Form.:
C26H23N3O4
Mol. Mass.:
441.4785
SMILES:
Cc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(cc(c2o1)C(C)(C)O)C#N
Structure:
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