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Target
LL-diaminopimelate aminotransferase, chloroplastic
Ligand
BDBM50181728
Substrate
n/a
Meas. Tech.
ChEMBL_613320 (CHEMBL1074257)
IC50
200000±n/a nM
Citation
 Fan, C; Clay, MD; Deyholos, MK; Vederas, JC Exploration of inhibitors for diaminopimelate aminotransferase. Bioorg Med Chem 18:2141-2151 (2010) [PubMed]  Article 
Target
Name:
LL-diaminopimelate aminotransferase, chloroplastic
Synonyms:
2.6.1.83 | AGD2 | AGD2 | AtDAP-AT | DAP | DAP-AT | DAP-aminotransferase | DAPAT_ARATH | LL-DAP-aminotransferase | LL-diaminopimelate aminotransferase, chloroplastic | Protein ABERRANT GROWTH AND DEATH 2
Type:
PROTEIN
Mol. Mass.:
50399.19
Organism:
Arabidopsis thaliana
Description:
ChEMBL_109120
Residue:
461
Sequence:
MSSTHQLVSSMISSSSSTFLAPSNFNLRTRNACLPMAKRVNTCKCVATPQEKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK
  
Inhibitor
Name:
BDBM50181728
Synonyms:
(Z)-5-(4-Chlorobenzylidene)-3-ethyl-2-thioxothiazolidin-4-one | 5-(4-chlorobenzylidene)-3-ethyl-4-oxo-2-thionothiazolidine | CHEMBL202173
Type:
Small organic molecule
Emp. Form.:
C12H10ClNOS2
Mol. Mass.:
283.797
SMILES:
CCN1C(=S)S\C(=C/c2ccc(Cl)cc2)C1=O
Structure:
Search PDB for entries with ligand similarity: