Reaction Details Report a problem with these data
Target
Matrix protein 2
Ligand
BDBM50482317
Substrate
n/a
Meas. Tech.
ChEMBL_639626 (CHEMBL1175304)
Kd
1500±n/a nM
Citation
 Eleftheratos, S; Spearpoint, P; Ortore, G; Kolocouris, A; Martinelli, A; Martin, S; Hay, A Interaction of aminoadamantane derivatives with the influenza A virus M2 channel-docking using a pore blocking model. Bioorg Med Chem Lett 20:4182-7 (2010) [PubMed]  Article 
Target
Name:
Matrix protein 2
Synonyms:
M | M2_I000F | Matrix protein 2 | Proton channel protein M2
Type:
PROTEIN
Mol. Mass.:
11173.62
Organism:
Influenza A virus
Description:
ChEMBL_117202
Residue:
97
Sequence:
MSLLTEVETPTRNGWECSCSDSSDPLVIAASIIGILHFILWILDRLFFKCIYRRLKYGLKRGPSTEGVPKSMREEYRQEQQNAVDVDDGHFVNIELE
  
Inhibitor
Name:
BDBM50482317
Synonyms:
CHEMBL45179
Type:
Small organic molecule
Emp. Form.:
C14H23N
Mol. Mass.:
205.3391
SMILES:
CC1CCC2(N1)C1CC3CC(C1)CC2C3 |TLB:5:4:8.7.14:10.11.12,3:4:7:10.11.9,THB:3:4:8.7.14:10.11.12,12:13:7:10.11.9,12:10:7:4.13.14,9:10:4:8.7.14,9:8:4:10.11.12,(6.09,-1.27,;4.57,-.9,;3.98,.53,;2.46,.41,;2.11,-1.08,;3.42,-1.9,;.71,-.51,;-.65,-.99,;-.63,-2.48,;-1.84,-3.75,;-.33,-3.33,;-.34,-1.74,;1.08,-3.91,;2.09,-2.63,;.69,-2.97,)|
Structure:
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