Reaction Details Report a problem with these data
Target
Killer cell lectin-like receptor subfamily B member 1A
Ligand
BDBM18351
Substrate
n/a
Meas. Tech.
ChEMBL_643486 (CHEMBL1212350)
IC50
10000±n/a nM
Citation
 Catelani, G; D'Andrea, F; Griselli, A; Guazzelli, L; Nemcová, P; Bezouska, K; Krenek, K; Kren, V Deoxynojirimycin and its hexosaminyl derivatives bind to natural killer cell receptors rNKR-P1A and hCD69. Bioorg Med Chem Lett 20:4645-8 (2010) [PubMed]  Article 
Target
Name:
Killer cell lectin-like receptor subfamily B member 1A
Synonyms:
Antigen 3.2.3 | CD161 antigen-like family member A | CD_antigen=CD161a | KLRBA_RAT | Killer cell lectin-like receptor subfamily B member 1A | Klrb1a | NKR-P1 3.2.3 | NKR-P1A | Natural killer cell surface protein P1-3.2.3 | Nkrp1a
Type:
PROTEIN
Mol. Mass.:
24555.68
Organism:
Rattus norvegicus
Description:
ChEMBL_109233
Residue:
223
Sequence:
MDTARVYLSLKPSKTAAGAQCVSPPSLPPDACRCPRSHRLALKLSCAGLILLVLALVGMSILVRVLVQKPSVEPCRVLIQENLSKTGSPAKLKCPKDWLSHRDKCFHVSQTSITWKESLADCGGKGATLLLVQDQEELRFLRNLTKRISSSFWIGLSYTLSDENWKWINGSTLNSDVLSITGDTEKDSCASVSQDKVLSESCDSDNIWVCQKELKCECMCNDS
  
Inhibitor
Name:
BDBM18351
Synonyms:
(2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol, 10 | (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol | 1-Deoxynojirimycin | 1-deoxynojirimycin (DNJ) | CHEMBL307429 | US20230339856, Compound DNJ | US9181184, 1 | dNM
Type:
natural product
Emp. Form.:
C6H13NO4
Mol. Mass.:
163.1717
SMILES:
OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
Structure:
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