Reaction Details Report a problem with these data
Target
Protease
Ligand
BDBM50483337
Substrate
n/a
Meas. Tech.
ChEMBL_715372 (CHEMBL1664701)
Ki
0.068000±n/a nM
Citation
Ghosh, AK; Chapsal, BD; Baldridge, A; Steffey, MP; Walters, DE; Koh, Y; Amano, M; Mitsuya, H Design and synthesis of potent HIV-1 protease inhibitors incorporating hexahydrofuropyranol-derived high affinity P(2) ligands: structure-activity studies and biological evaluation. J Med Chem 54:622-34 (2011) [PubMed] Article
More Info.:
Target
Name:
Protease
Synonyms:
n/a
Type:
Enzyme
Mol. Mass.:
10904.79
Organism:
Human immunodeficiency virus 1 (HIV-1)
Description:
Q9YQ12
Residue:
99
Sequence:
PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF