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Target
Chymotrypsin-like protease CTRL-1
Ligand
BDBM50484487
Substrate
n/a
Meas. Tech.
ChEMBL_794322 (CHEMBL1932244)
IC50
390±n/a nM
Citation
 Akaji, K; Konno, H; Mitsui, H; Teruya, K; Shimamoto, Y; Hattori, Y; Ozaki, T; Kusunoki, M; Sanjoh, A Structure-based design, synthesis, and evaluation of peptide-mimetic SARS 3CL protease inhibitors. J Med Chem 54:7962-73 (2011) [PubMed]  Article 
Target
Name:
Chymotrypsin-like protease CTRL-1
Synonyms:
CTRL | CTRL1 | CTRL_HUMAN
Type:
PROTEIN
Mol. Mass.:
28008.18
Organism:
Homo sapiens (Human)
Description:
ChEMBL_49606
Residue:
264
Sequence:
MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQYWGSSITDSMICAGGAGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAVYTRVSKFSTWINQVIAYN
  
Inhibitor
Name:
BDBM50484487
Synonyms:
CHEMBL1929018 | acs.jmedchem.1c00409_ST.150
Type:
Small organic molecule
Emp. Form.:
C28H39N7O7
Mol. Mass.:
585.652
SMILES:
CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C=O |r|
Structure:
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