Reaction Details Report a problem with these data
Target
Polyphenol oxidase 2
Ligand
BDBM50484892
Substrate
n/a
Meas. Tech.
ChEMBL_812370 (CHEMBL2014106)
IC50
>100000±n/a nM
Citation
 Cho, JC; Rho, HS; Baek, HS; Ahn, SM; Woo, BY; Hong, YD; Cheon, JW; Heo, JM; Shin, SS; Park, YH; Suh, KD Depigmenting activity of new kojic acid derivative obtained as a side product in the synthesis of cinnamate of kojic acid. Bioorg Med Chem Lett 22:2004-7 (2012) [PubMed]  Article 
Target
Name:
Polyphenol oxidase 2
Synonyms:
Monophenol monooxygenase | Monophenol oxidase | PPO2 | PPO2_AGABI | Tyrosinase
Type:
Protein
Mol. Mass.:
63923.66
Organism:
Agaricus bisporus (Common mushroom)
Description:
O42713
Residue:
556
Sequence:
MSLIATVGPTGGVKNRLNIVDFVKNEKFFTLYVRSLELLQAKEQHDYSSFFQLAGIHGLPFTEWAKERPSMNLYKAGYCTHGQVLFPTWHRTYLSVLEQILQGAAIEVAKKFTSNQTDWVQAAQDLRQPYWDWGFELMPPDEVIKNEEVNITNYDGKKISVKNPILRYHFHPIDPSFKPYGDFATWRTTVRNPDRNRREDIPGLIKKMRLEEGQIREKTYNMLKFNDAWERFSNHGISDDQHANSLESVHDDIHVMVGYGKIEGHMDHPFFAAFDPIFWLHHTNVDRLLSLWKAINPDVWVTSGRNRDGTMGIAPNAQINSETPLEPFYQSGDKVWTSASLADTARLGYSYPDFDKLVGGTKELIRDAIDDLIDERYGSKPSSGARNTAFDLLADFKGITKEHKEDLKMYDWTIHVAFKKFELKESFSLLFYFASDGGDYDQENCFVGSINAFRGTAPETCANCQDNENLIQEGFIHLNHYLARDLESFEPQDVHKFLKEKGLSYKLYSRGDKPLTSLSVKIEGRPLHLPPGEHRPKYDHTQARVVFDDVAVHVIN
  
Inhibitor
Name:
BDBM50484892
Synonyms:
CHEMBL2012555
Type:
Small organic molecule
Emp. Form.:
C22H16O10
Mol. Mass.:
440.3564
SMILES:
Oc1coc(COc2coc(COC(=O)\C=C\c3ccc4OCOc4c3)cc2=O)cc1=O
Structure:
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