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Target
Anthrax toxin receptor 2
Ligand
BDBM50485548
Substrate
n/a
Meas. Tech.
ChEMBL_835813 (CHEMBL2071924)
IC50
600±n/a nM
Citation
 Cao, S; Cryan, L; Habeshian, KA; Murillo, C; Tamayo-Castillo, G; Rogers, MS; Clardy, J Phenolic compounds as antiangiogenic CMG2 inhibitors from Costa Rican endophytic fungi. Bioorg Med Chem Lett 22:5885-8 (2012) [PubMed]  Article 
Target
Name:
Anthrax toxin receptor 2
Synonyms:
ANTR2_HUMAN | ANTXR2 | Anthrax toxin receptor 2 | CMG-2 | CMG2 | Capillary morphogenesis gene 2 protein
Type:
PROTEIN
Mol. Mass.:
53667.55
Organism:
Homo sapiens
Description:
ChEMBL_118453
Residue:
489
Sequence:
MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLDFEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLSGRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGGKSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPEETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGDEVCIWECIEKELTA
  
Inhibitor
Name:
BDBM50485548
Synonyms:
CHEBI:1369 | CHEMBL559789
Type:
Small organic molecule
Emp. Form.:
C10H8O4
Mol. Mass.:
192.1681
SMILES:
Cc1cc2cc(O)cc(O)c2c(=O)o1
Structure:
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