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Target
Solute carrier family 22 member 1
Ligand
BDBM50420181
Substrate
n/a
Meas. Tech.
ChEMBL_836354 (CHEMBL2076518)
IC50
180±n/a nM
Citation
 Gorboulev, V; Volk, C; Arndt, P; Akhoundova, A; Koepsell, H Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate. Mol Pharmacol 56:1254-61 (1999) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 1
Synonyms:
Adrenaline alpha1 | Oct1 | Organic cation transporter 1 | S22A1_RAT | Slc22a1 | Solute carrier family 22 member 1 | adrenergic Alpha1 | rOCT1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
61538.40
Organism:
RAT
Description:
Adrenaline alpha1 0 RAT::Q63089
Residue:
556
Sequence:
MPTVDDVLEQVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPGHYCQNPGVAELSQRCGWSQAEELNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLVANRSQLPLGPCEHGWVYDTPGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCLLVTTLVTSVSGVLTAVAPDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQMAFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTRAVRIMEQIAQKNGKVPPADLKMLCLEEDASEKRSPSFADLFRTPNLRKHTVILMYLWFSCAVLYQGLIMHVGATGANLYLDFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVTGAACLLMIFIPHELHWLNVTLACLGRMGATIVLQMVCLVNAELYPTFIRNLGMMVCSALCDLGGIFTPFMVFRLMEVWQALPLILFGVLGLTAGAMTLLLPETKGVALPETIEEAENLGRRKSKAKENTIYLQVQTGKSSST
  
Inhibitor
Name:
BDBM50420181
Synonyms:
CHEMBL2074704
Type:
Small organic molecule
Emp. Form.:
C20H44N
Mol. Mass.:
298.5695
SMILES:
CCCCC[N+](CCCCC)(CCCCC)CCCCC
Structure:
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