Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 4
Ligand
BDBM50103595
Substrate
n/a
Meas. Tech.
ChEMBL_835945 (CHEMBL2077083)
IC50
1500000±n/a nM
Citation
 Wu, X; George, RL; Huang, W; Wang, H; Conway, SJ; Leibach, FH; Ganapathy, V Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta. Biochim Biophys Acta 1466:315-27 (2000) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 4
Synonyms:
Octn1 | Organic cation/carnitine transporter 1 | S22A4_RAT | Slc22a4 | Solute carrier family 22 member 4
Type:
PROTEIN
Mol. Mass.:
62362.68
Organism:
Rattus norvegicus
Description:
ChEMBL_104608
Residue:
553
Sequence:
MRDYDEVIAFLGDWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCLVPHTVNLSSAWRNHSIPLETKDGRQVPQSCRRYRLATIANFSALGLEPGLDVDLEQLEQESCLDGWEYSKDVFLSTIVTEWNLVCEDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGFSFVQIFSTNWEMFTVLFAIVGMGQISNYVVAFILGTEILSKSVRILFSTLGVCTFFAIGYMVLPLFAYFIRDWRMLLLALTLPGLFCVPLWWFIPESPRWLISQRRFEEAEQIIQKAAKMNGIMAPAVIFDPLELQELNSLKQQKVFILDLFKTRNIATITVMSVMLWMLTSVGYFALSLNVPNLHGDVYLNCFLSGLIEVPAYFTAWLLLRTLPRRYIIAGVLFWGGGVLLLVQVVPEDYNFVSIGLVMLGKFGVTSAFSMLYVFTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLIGIITLFFPESFGVTLPENLEQMQKVRGFRCGKKSTVSMDREENPKVLITAF
  
Inhibitor
Name:
BDBM50103595
Synonyms:
Brumetadina | CHEBI:3699 | Cimetidine | Tagamet | Tagamet HB | Tagamet HB 200 | Valmagen
Type:
Small organic molecule
Emp. Form.:
C10H16N6S
Mol. Mass.:
252.339
SMILES:
CN\C(NC#N)=N/CCSCc1nc[nH]c1C
Structure:
Search PDB for entries with ligand similarity: