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Target
Neuraminidase
Ligand
BDBM50486064
Substrate
n/a
Meas. Tech.
ChEMBL_884357 (CHEMBL2210795)
IC50
0.700000±n/a nM
Citation
 Liu, KC; Fang, JM; Jan, JT; Cheng, TJ; Wang, SY; Yang, ST; Cheng, YS; Wong, CH Enhanced anti-influenza agents conjugated with anti-inflammatory activity. J Med Chem 55:8493-501 (2012) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
NA | NRAM_I33A0
Type:
PROTEIN
Mol. Mass.:
49687.56
Organism:
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus(strain A/WS/1933 H1N1))
Description:
ChEMBL_881601
Residue:
453
Sequence:
MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVAGQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWDPNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETIWTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
  
Inhibitor
Name:
BDBM50486064
Synonyms:
CHEMBL2205840
Type:
Small organic molecule
Emp. Form.:
C27H33N5O11
Mol. Mass.:
603.5778
SMILES:
[H][C@]1(OC(=C[C@H](NC(N)=N)[C@H]1NC(C)=O)C(O)=O)[C@H](OC(=O)NCCCOC(=O)c1ccc2ccccc2c1O)[C@H](O)CO |r,c:3|
Structure:
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