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Target
Alpha-glucosidase MAL62
Ligand
BDBM50486905
Substrate
n/a
Meas. Tech.
ChEMBL_903251 (CHEMBL3047160)
IC50
10592537252±n/a nM
Citation
  TBA Med Chem Res 21:3984-3993 (2012)    Article 
Target
Name:
Alpha-glucosidase MAL62
Synonyms:
MAL62 | MAL62_YEASX | MAL6S
Type:
PROTEIN
Mol. Mass.:
68174.43
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_942538
Residue:
584
Sequence:
MTISDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHPNWGSHNGPRIHEYHQELHRFMKNRVKDGREIMRVGEVAHGSDNALYTSAARYEVSEVFSFTHVEVGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFFLNESFEQGINVEQESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNFSGEEIEFSLPREGASLSFILGNYDDTDVSSRVLKPWEGRIYLVK
  
Inhibitor
Name:
BDBM50486905
Synonyms:
CHEMBL2235441
Type:
Small organic molecule
Emp. Form.:
C29H36O4
Mol. Mass.:
448.5937
SMILES:
[#6]\[#6]=[#6]/[#6]-c1c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c(-[#8])cc1-[#6]-1-[#6]-[#6]-c2cc(c(-[#8])cc2-[#8]-1)C([#6])([#6])[#6]=[#6]
Structure:
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