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Target
Protoporphyrinogen oxidase
Ligand
BDBM50487112
Substrate
n/a
Meas. Tech.
ChEMBL_907345 (CHEMBL3065646)
IC50
<3890±n/a nM
Citation
 Li, HB; Zhu, YQ; Song, XW; Hu, FZ; Liu, B; Li, YH; Niu, ZX; Liu, P; Wang, ZH; Song, HB; Zou, XM; Yang, HZ Novel protoporphyrinogen oxidase inhibitors: 3H-pyrazolo[3,4-d][1,2,3]triazin-4-one derivatives. J Agric Food Chem 56:9535-42 (2008) [PubMed]  Article 
Target
Name:
Protoporphyrinogen oxidase
Synonyms:
1.3.3.4 | Protoporphyrinogen oxidase
Type:
PROTEIN
Mol. Mass.:
56841.56
Organism:
Zea mays
Description:
ChEMBL_105521
Residue:
535
Sequence:
MVAATATAMATAASPLLNGTRIPARLRHRGLSVRCAAVAGGAAEAPASTGARLSADCVVVGGGISGLCTAQALATRHGVGDVLVTEARARPGGNITTVERPEEGYLWEEGPNSFQPSDPVLTMAVDSGLKDDLVFGDPNAPRFVLWEGKLRPVPSKPADLPFFDLMSIPGKLRAGLGALGIRPPPPGREESVEEFVRRNLGAEVFERLIEPFCSGVYAGDPSKLSMKAAFGKVWRLEETGGSIIGGTIKTIQERSKNPKPPRDARLPKPKGQTVASFRKGLAMLPNAITSSLGSKVKLSWKLTSITKSDDKGYVLEYETPEGVVSVQAKSVIMTIPSYVASNILRPLSSDAADALSRFYYPPVAAVTVSYPKEAIRKECLIDGELQGFGQLHPRSQGVETLGTIYSSSLFPNRAPDGRVLLLNYIGGATNTGIVSKTESELVEAVDRDLRKMLINSTAVDPLVLGVRVWPQAIPQFLVGHLDLLEAAKAALDRGGYDGLFLGGNYVAGVALGRCVEGAYESASQISDFLTKYAYK
  
Inhibitor
Name:
BDBM50487112
Synonyms:
CHEMBL2253328
Type:
Small organic molecule
Emp. Form.:
C16H13ClFN5O2
Mol. Mass.:
361.758
SMILES:
Fc1cc(Cl)c(OCC=C)cc1-n1nnc2nn(CC=C)cc2c1=O
Structure:
Search PDB for entries with ligand similarity: