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Target
Delta(14)-sterol reductase
Ligand
BDBM50003027
Substrate
n/a
Meas. Tech.
ChEMBL_909060 (CHEMBL3049784)
IC50
300±n/a nM
Citation
 Taton, M; Benveniste, P; Rahier, A Microsomal delta 8,14-sterol delta 14-reductase in higher plants. Characterization and inhibition by analogues of a presumptive carbocationic intermediate of the reduction reaction. Eur J Biochem 185:605-14 (1989) [PubMed]  Article 
Target
Name:
Delta(14)-sterol reductase
Synonyms:
100281352 | Delta(14)-sterol reductase
Type:
PROTEIN
Mol. Mass.:
41580.42
Organism:
Zea mays
Description:
ChEMBL_106555
Residue:
370
Sequence:
MEAAAAVLPTLVPSGSAVVVLLAYLGYLAAAGAILPGKLVDGALLPDSSRLHYRCNGLLSLLLLLGLSAFGVYMGWMSPTVVADMGLELLSVTFIFSVIVSFALYIAGIKSGHKSSSLRPHVSGSFMQDWWFGVQLNPHFMEVDLKFFFVRAGMMAWLFINLSLFAKSYFAGSANLSVILYQFFCAWYIIDYFVHEEFMTSTWDIIAERLGFMLVFGDLVFIPFTFTIQGWWLLKNKVELSLLSGLANLCIFLIGYLVFRGANKQKHVFKKDPKAPIWGKPPKVVGGKLLASGYWGIARHCNYLGDLLLALSFSLPCGVSSVVPYFYPTYLLILLVLRERRDEARCSQKYREIWAEYCKLVPWRILPYVY
  
Inhibitor
Name:
BDBM50003027
Synonyms:
(4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5,9-trimethyl-decyl)-decahydro-isoquinolin-6-ol | 5,8a-Dimethyl-2-(1,5,9-trimethyl-decyl)-decahydro-isoquinolin-6-ol | CHEMBL17470
Type:
Small organic molecule
Emp. Form.:
C24H47NO
Mol. Mass.:
365.6361
SMILES:
CC(C)CCCC(C)CCCC(C)N1CC[C@H]2[C@H](C)[C@@H](O)CC[C@]2(C)C1
Structure:
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