Reaction Details Report a problem with these data
Target
Delta(14)-sterol reductase
Ligand
BDBM50487252
Substrate
n/a
Meas. Tech.
ChEMBL_909060 (CHEMBL3049784)
IC50
30±n/a nM
Citation
 Taton, M; Benveniste, P; Rahier, A Microsomal delta 8,14-sterol delta 14-reductase in higher plants. Characterization and inhibition by analogues of a presumptive carbocationic intermediate of the reduction reaction. Eur J Biochem 185:605-14 (1989) [PubMed]  Article 
Target
Name:
Delta(14)-sterol reductase
Synonyms:
100281352 | Delta(14)-sterol reductase
Type:
PROTEIN
Mol. Mass.:
41580.42
Organism:
Zea mays
Description:
ChEMBL_106555
Residue:
370
Sequence:
MEAAAAVLPTLVPSGSAVVVLLAYLGYLAAAGAILPGKLVDGALLPDSSRLHYRCNGLLSLLLLLGLSAFGVYMGWMSPTVVADMGLELLSVTFIFSVIVSFALYIAGIKSGHKSSSLRPHVSGSFMQDWWFGVQLNPHFMEVDLKFFFVRAGMMAWLFINLSLFAKSYFAGSANLSVILYQFFCAWYIIDYFVHEEFMTSTWDIIAERLGFMLVFGDLVFIPFTFTIQGWWLLKNKVELSLLSGLANLCIFLIGYLVFRGANKQKHVFKKDPKAPIWGKPPKVVGGKLLASGYWGIARHCNYLGDLLLALSFSLPCGVSSVVPYFYPTYLLILLVLRERRDEARCSQKYREIWAEYCKLVPWRILPYVY
  
Inhibitor
Name:
BDBM50487252
Synonyms:
CHEMBL2253388
Type:
Small organic molecule
Emp. Form.:
C28H45NO
Mol. Mass.:
411.663
SMILES:
CC(C)C(=C)CC[C@@H](C)[C@H]1CCN=C2C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C[C@@H]1CC3 |r,c:14,t:12|
Structure:
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