Reaction Details Report a problem with these data
Target
Sterol-8,7-isomerase
Ligand
BDBM50003027
Substrate
n/a
Meas. Tech.
ChEMBL_909058 (CHEMBL3049782)
IC50
200±n/a nM
Citation
 Taton, M; Benveniste, P; Rahier, A Microsomal delta 8,14-sterol delta 14-reductase in higher plants. Characterization and inhibition by analogues of a presumptive carbocationic intermediate of the reduction reaction. Eur J Biochem 185:605-14 (1989) [PubMed]  Article 
Target
Name:
Sterol-8,7-isomerase
Synonyms:
Sterol-8,7-isomerase
Type:
PROTEIN
Mol. Mass.:
24949.56
Organism:
Zea mays
Description:
ChEMBL_106636
Residue:
221
Sequence:
MAAAASMGHPYAPAELDLPGFVPLKLSQVEILVSYLGASVFVFLAVWLVSGRCVRLSKTDRLLMCWWAFTGLTHIMIEGPFVFTPDFFKKENPNFFDEVWKEYSKGDSRYVARDTATVTVEGITAVLEGPASLLAVYAIASRKSFSHILQFAVCLGQLYGCLVYFITAYLDGFNFWVGPFYFWAYFIGANSFWIWIPMLIAIRSWKKTCAAFQAVKVKKTK
  
Inhibitor
Name:
BDBM50003027
Synonyms:
(4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5,9-trimethyl-decyl)-decahydro-isoquinolin-6-ol | 5,8a-Dimethyl-2-(1,5,9-trimethyl-decyl)-decahydro-isoquinolin-6-ol | CHEMBL17470
Type:
Small organic molecule
Emp. Form.:
C24H47NO
Mol. Mass.:
365.6361
SMILES:
CC(C)CCCC(C)CCCC(C)N1CC[C@H]2[C@H](C)[C@@H](O)CC[C@]2(C)C1
Structure:
Search PDB for entries with ligand similarity: