Reaction Details Report a problem with these data
Target
Delta(14)-sterol reductase
Ligand
BDBM50487253
Substrate
n/a
Meas. Tech.
ChEMBL_909060 (CHEMBL3049784)
IC50
25000±n/a nM
Citation
 Taton, M; Benveniste, P; Rahier, A Microsomal delta 8,14-sterol delta 14-reductase in higher plants. Characterization and inhibition by analogues of a presumptive carbocationic intermediate of the reduction reaction. Eur J Biochem 185:605-14 (1989) [PubMed]  Article 
Target
Name:
Delta(14)-sterol reductase
Synonyms:
100281352 | Delta(14)-sterol reductase
Type:
PROTEIN
Mol. Mass.:
41580.42
Organism:
Zea mays
Description:
ChEMBL_106555
Residue:
370
Sequence:
MEAAAAVLPTLVPSGSAVVVLLAYLGYLAAAGAILPGKLVDGALLPDSSRLHYRCNGLLSLLLLLGLSAFGVYMGWMSPTVVADMGLELLSVTFIFSVIVSFALYIAGIKSGHKSSSLRPHVSGSFMQDWWFGVQLNPHFMEVDLKFFFVRAGMMAWLFINLSLFAKSYFAGSANLSVILYQFFCAWYIIDYFVHEEFMTSTWDIIAERLGFMLVFGDLVFIPFTFTIQGWWLLKNKVELSLLSGLANLCIFLIGYLVFRGANKQKHVFKKDPKAPIWGKPPKVVGGKLLASGYWGIARHCNYLGDLLLALSFSLPCGVSSVVPYFYPTYLLILLVLRERRDEARCSQKYREIWAEYCKLVPWRILPYVY
  
Inhibitor
Name:
BDBM50487253
Synonyms:
TRIDEMORPH
Type:
Small organic molecule
Emp. Form.:
C19H39NO
Mol. Mass.:
297.5191
SMILES:
CCCCCCCCCCCCCN1CC(C)OC(C)C1
Structure:
Search PDB for entries with ligand similarity: