Reaction Details Report a problem with these data
Target
Delta(14)-sterol reductase
Ligand
BDBM50487258
Substrate
n/a
Meas. Tech.
ChEMBL_909060 (CHEMBL3049784)
IC50
80±n/a nM
Citation
 Taton, M; Benveniste, P; Rahier, A Microsomal delta 8,14-sterol delta 14-reductase in higher plants. Characterization and inhibition by analogues of a presumptive carbocationic intermediate of the reduction reaction. Eur J Biochem 185:605-14 (1989) [PubMed]  Article 
Target
Name:
Delta(14)-sterol reductase
Synonyms:
100281352 | Delta(14)-sterol reductase
Type:
PROTEIN
Mol. Mass.:
41580.42
Organism:
Zea mays
Description:
ChEMBL_106555
Residue:
370
Sequence:
MEAAAAVLPTLVPSGSAVVVLLAYLGYLAAAGAILPGKLVDGALLPDSSRLHYRCNGLLSLLLLLGLSAFGVYMGWMSPTVVADMGLELLSVTFIFSVIVSFALYIAGIKSGHKSSSLRPHVSGSFMQDWWFGVQLNPHFMEVDLKFFFVRAGMMAWLFINLSLFAKSYFAGSANLSVILYQFFCAWYIIDYFVHEEFMTSTWDIIAERLGFMLVFGDLVFIPFTFTIQGWWLLKNKVELSLLSGLANLCIFLIGYLVFRGANKQKHVFKKDPKAPIWGKPPKVVGGKLLASGYWGIARHCNYLGDLLLALSFSLPCGVSSVVPYFYPTYLLILLVLRERRDEARCSQKYREIWAEYCKLVPWRILPYVY
  
Inhibitor
Name:
BDBM50487258
Synonyms:
CHEMBL17413
Type:
Small organic molecule
Emp. Form.:
C18H27NO
Mol. Mass.:
273.4131
SMILES:
[H][C@@]12CCN(Cc3ccccc3)C[C@@]1(C)CC[C@H](O)[C@H]2C
Structure:
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