Reaction Details
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Alpha-1A adrenergic receptor
Ligand
BDBM50474630
Substrate
n/a
Meas. Tech.
ChEMBL_911064 (CHEMBL3056711)
EC50
17±n/a nM
Citation
TBA Med Chem Res 13:134-148 (2004) Article More Info.:
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
ADA1A_RABIT | ADRA1A | ADRA1C | adrenergic Alpha1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51390.87
Organism:
RABBIT
Description:
adrenergic Alpha1 0 RABBIT::O02824
Residue:
466
Sequence:
MVFLSGNASDSSNCTHPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIISLCVISIDRYIGVSYPLRYPTIVTQRRGLRALLCVWAFSLVISVGPLFGWRQPAPDDETICQINEEPGYVLFSALGSFYVPLTIILAMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGVASAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPPETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLKIQCLRRKQSSKHALGYTLHAPSQALEGQHKDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPRGSARITVPKDQSACTTARVRSKSFLQVCCCVGPSTPNPGENHQVPTIKIHTISLSENGEEV
Inhibitor
Name:
BDBM50474630
Synonyms:
CHEMBL108804
Type:
Small organic molecule
Emp. Form.:
C14H17N3O3S
Mol. Mass.:
307.368
SMILES:
CS(=O)(=O)Nc1c(O)ccc2C(CCCc12)c1c[nH]cn1
Structure:
