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Target
Beta-2 adrenergic receptor
Ligand
BDBM50156250
Substrate
n/a
Meas. Tech.
ChEMBL_909575 (CHEMBL3059445)
EC50
29±n/a nM
Citation
 Senthil Kumar, P; Bharatam, PV Comparative 3D QSAR study on ?(1)-, ?(2)-, and ?(3)-adrenoceptor agonists. Med Chem Res 19:1121-1140 (2010) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50156250
Synonyms:
CHEMBL361505 | Thiophene-2-sulfonic acid (3-{(R)-1-hydroxy-2-[(R)-2-(7-methoxy-1H-indol-3-yl)-1-methyl-ethylamino]-ethyl}-phenyl)-amide
Type:
Small organic molecule
Emp. Form.:
C24H27N3O4S2
Mol. Mass.:
485.619
SMILES:
COc1cccc2c(C[C@@H](C)NC[C@H](O)c3cccc(NS(=O)(=O)c4cccs4)c3)c[nH]c12
Structure:
Search PDB for entries with ligand similarity: