Reaction Details
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Aldo-keto reductase family 1 member B1
Ligand
BDBM50487936
Substrate
n/a
Meas. Tech.
ChEMBL_912706 (CHEMBL3055410)
IC50
1.3±n/a nM
Citation
TBA Med Chem Res 21:1665-1676 (2012) Article More Info.:
Target
Name:
Aldo-keto reductase family 1 member B1
Synonyms:
ALDR_RAT | Akr1b1 | Akr1b4 | Aldr1 | Aldose reductase
Type:
PROTEIN
Mol. Mass.:
35797.87
Organism:
Rat
Description:
ChEMBL_1512484
Residue:
316
Sequence:
MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFDFELSNEDMATLLSYNRNWRVCALMSCAKHKDYPFHAEV
Inhibitor
Name:
BDBM50487936
Synonyms:
CHEBI:48480 | CHEMBL2261578
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
