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Target
Nicotinic acetylcholine receptor alpha 5 subunit
Ligand
BDBM50487983
Substrate
n/a
Meas. Tech.
ChEMBL_917697 (CHEMBL3052328)
IC50
7.1±n/a nM
Citation
 Zhang, A; Kayser, H; Maienfisch, P; Casida, JE Insect nicotinic acetylcholine receptor: conserved neonicotinoid specificity of [(3)H]imidacloprid binding site. J Neurochem 75:1294-303 (2000) [PubMed]  Article 
Target
Name:
Nicotinic acetylcholine receptor alpha 5 subunit
Synonyms:
Nicotinic acetylcholine receptor alpha 5 subunit | nAChRalpha5
Type:
PROTEIN
Mol. Mass.:
88489.00
Organism:
Musca domestica
Description:
ChEMBL_106552
Residue:
781
Sequence:
MMWEMLILWAVHLSLTAIATLYANVRTALSQTAQQIVRAVIAATTLPIIQRIQQQQHETEKQQQQLQHGKHVEDIHLPAAGARYASASSSRLPPSSADATIWPRAPPELPQTEKLSSAPPPPSSSSTLLMQTKPAHKKPVHGRNFPPQQKNRMQPVSHLQYQQQQQQQLSLPSPAEPQPQHYKQQQQQQGQERLGQQVNINNITSSSNGGNTCSSNSFTATTSIAATTTTSILTLWQHCHRRYRPHQLLPLLTTKGLNKYSWIFLLIYLNLSAKVCLAGYNEKRLLHDLLDTYNTLERPVLNESDPLQLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGIKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDETGGDISSYVLNGEWELLGVPGKRNEIYYNCCPEPYIDITFAIIIRRRTLYYFFNLIIPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNADTHEMSEWIRVVFLCWLPWILRMHRPGRPIIMDFTSTPCSDTSSERKHQILSDVELKERSSKSLLANVLDIDDDFRNVRPMTPGGTLPHNPAFYRTVYGYLENLQGDDGSIGPIGSTRMPDAVTHHTCIKTQTEYELSLILKEIRFITDQLRKEDEENGIANDWKFAAMVVDRLCLIIFTMFAILATIAVLLSAPHVIVS
  
Inhibitor
Name:
BDBM50487983
Synonyms:
CHEMBL148390
Type:
Small organic molecule
Emp. Form.:
C8H10ClN5O2
Mol. Mass.:
243.65
SMILES:
C\N=C(/NCc1ccc(Cl)nc1)N[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: