Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 5
Ligand
BDBM50197768
Substrate
n/a
Meas. Tech.
ChEMBL_922573 (CHEMBL3077270)
IC50
1300±n/a nM
Citation
  TBA Med Chem Res 22:1356-1364 (2013)    Article 
Target
Name:
C-C chemokine receptor type 5
Synonyms:
C-C CKR-5 | C-C chemokine receptor type 5 | CC-CKR-5 | CCR-5 | CCR5 | CCR5/mu opioid receptor complex | CCR5_HUMAN | CD_antigen=CD195 | CHEMR13 | CMKBR5 | HIV-1 fusion coreceptor
Type:
Enzyme
Mol. Mass.:
40540.21
Organism:
Homo sapiens (Human)
Description:
P51681
Residue:
352
Sequence:
MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
  
Inhibitor
Name:
BDBM50197768
Synonyms:
CHEMBL241251 | methyl 4-{[2-((E)-{[amino(imino)methyl]hydrazono}methyl)-4-bromophenoxy]methyl}benzoate
Type:
Small organic molecule
Emp. Form.:
C17H17BrN4O3
Mol. Mass.:
405.246
SMILES:
[#6]-[#8]-[#6](=O)-c1ccc(-[#6]-[#8]-c2ccc(Br)cc2-[#6]=[#7]\[#7]=[#6](\[#7])-[#7])cc1 |w:17.17|
Structure:
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