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Target
Ecdysone receptor
Ligand
BDBM50488468
Substrate
n/a
Meas. Tech.
ChEMBL_925676 (CHEMBL3070722)
EC50
4.4±n/a nM
Citation
 Soin, T; Swevers, L; Kotzia, G; Iatrou, K; Janssen, CR; Rougé, P; Harada, T; Nakagawa, Y; Smagghe, G Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays. Pest Manag Sci 66:1215-29 (2010) [PubMed]  Article 
Target
Name:
Ecdysone receptor
Synonyms:
20-hydroxy-ecdysone receptor | 20E receptor | ECR_BOMMO | EcR | EcRH | Ecdysteroid receptor | NR1H1 | Nuclear receptor subfamily 1 group H member 1
Type:
PROTEIN
Mol. Mass.:
68199.29
Organism:
Bombyx mori
Description:
ChEMBL_65456
Residue:
606
Sequence:
MRVENVDNVSFALNGRADEWCMSVETRLDSLVREKSEVKAYVGGCPSVITDAGAYDALFDMRRRWSNNGGFPLRMLEESSSEVTSSSALGLPPAMVMSPESLASPEYRALELWSYDDGITYNTAQSLLGACNMQQQQLQPQQPHPAPPTLPTMPLPMPPTTPKSENESMSSGREELSPASSINGCSADADARRQKKGPAPRQQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKNAVYICKFGHACEMDMYMRRKCQECRLKKCLAVGMRPECVIQEPSKNKDRQRQKKDKGILLPVSTTTVEDHMPPIMQCDPPPPEAARIHEVVPRYLSEKLMEQNRQKNIPPLSANQKSLIARLVWYQEGYEQPSDEDLKRVTQTWQSDEEDEESDLPFRQITEMTILTVQLIVEFAKGLPGFSKISQSDQITLLKASSSEVMMLRVARRYDAASDSVLFANNKAYTRDNYRQGGMAYVIEDLLHFCRCMFAMGMDNVHFALLTAIVIFSDRPGLEQPSLVEEIQRYYLNTLRIYIINQNSASSRCAVIYGRILSVLTELRTLGTQNSNMCISLKLKNRKLPPFLEEIWDVAEVATTHPTVLPPTNPVVL
  
Inhibitor
Name:
BDBM50488468
Synonyms:
CHEMBL2286448
Type:
Small organic molecule
Emp. Form.:
C26H31NO3
Mol. Mass.:
405.5292
SMILES:
Cc1cc(C)cc(c1)C(=O)C1(CCCCC1)NC(=O)c1ccc2OCCCc2c1C
Structure:
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