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Target
Protein ultraspiracle
Ligand
BDBM50488487
Substrate
n/a
Meas. Tech.
ChEMBL_925682 (CHEMBL3069808)
EC50
36308±n/a nM
Citation
 Soin, T; Swevers, L; Kotzia, G; Iatrou, K; Janssen, CR; Rougé, P; Harada, T; Nakagawa, Y; Smagghe, G Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays. Pest Manag Sci 66:1215-29 (2010) [PubMed]  Article 
Target
Name:
Protein ultraspiracle
Synonyms:
Cf1 | Chorion factor 1 | NR2B4 | Nuclear receptor subfamily 2 group B member 4 | USP_DROME | XR2C | usp
Type:
PROTEIN
Mol. Mass.:
55254.53
Organism:
Drosophila melanogaster
Description:
ChEMBL_106725
Residue:
508
Sequence:
MDNCDQDASFRLSHIKEEVKPDISQLNDSNNSSFSPKAESPVPFMQAMSMVHVLPGSNSASSNNNSAGDAQMAQAPNSAGGSAAAAVQQQYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGMKREAVQEERQRGARNAAGRLSASGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDFMTNSVSRDFSIERIIEAEQRAETQCGDRALTFLRVGPYSTVQPDYKGAVSALCQVVNKQLFQMVEYARMMPHFAQVPLDDQVILLKAAWIELLIANVAWCSIVSLDDGGAGGGGGGLGHDGSFERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAIFDRILSELSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAEIEMCREKVYACLDEHCRLEHPGDDGRFAQLLLRLPALRSISLKCQDHLFLFRITSDRPLEELFLEQLEAPPPPGLAMKLE
  
Inhibitor
Name:
BDBM50488487
Synonyms:
CHEMBL2286748
Type:
Small organic molecule
Emp. Form.:
C19H18ClN3O2
Mol. Mass.:
355.818
SMILES:
CC(C)(C)N(NC(=O)c1cccc(c1)C#N)C(=O)c1ccccc1Cl
Structure:
Search PDB for entries with ligand similarity: