Reaction Details Report a problem with these data
Target
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic
Ligand
BDBM50488599
Substrate
n/a
Meas. Tech.
ChEMBL_925783 (CHEMBL3069076)
IC50
1800±n/a nM
Citation
 Witschel, M; Röhl, F; Niggeweg, R; Newton, T In search of new herbicidal inhibitors of the non-mevalonate pathway. Pest Manag Sci 69:559-63 (2013) [PubMed]  Article 
Target
Name:
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic
Synonyms:
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase | AtMECT | AtMEPCT | ISPD | ISPD_ARATH | MCT | MECT | MEP cytidylyltransferase | MEPCT | MEPCT
Type:
PROTEIN
Mol. Mass.:
33935.84
Organism:
Arabidopsis thaliana
Description:
ChEMBL_105555
Residue:
302
Sequence:
MAMLQTNLGFITSPTFLCPKLKVKLNSYLWFSYRSQVQKLDFSKRVNRSYKRDALLLSIKCSSSTGFDNSNVVVKEKSVSVILLAGGQGKRMKMSMPKQYIPLLGQPIALYSFFTFSRMPEVKEIVVVCDPFFRDIFEEYEESIDVDLRFAIPGKERQDSVYSGLQEIDVNSELVCIHDSARPLVNTEDVEKVLKDGSAVGAAVLGVPAKATIKEVNSDSLVVKTLDRKTLWEMQTPQVIKPELLKKGFELVKSEGLEVTDDVSIVEYLKHPVYVSQGSYTNIKVTTPDDLLLAERILSEDS
  
Inhibitor
Name:
BDBM50488599
Synonyms:
CHEMBL2289492
Type:
Small organic molecule
Emp. Form.:
C18H14N4O3S
Mol. Mass.:
366.394
SMILES:
COc1ccc2nc(NC(=O)c3cc(n[nH]3)-c3ccccc3O)sc2c1
Structure:
Search PDB for entries with ligand similarity: