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Target
Chitin synthase 3
Ligand
BDBM49759
Substrate
n/a
Meas. Tech.
ChEMBL_932678 (CHEMBL3070435)
IC50
372392±n/a nM
Citation
  TBA Med Chem Res 22:1762-1772 (2013)    Article 
Target
Name:
Chitin synthase 3
Synonyms:
CAL1 | CHS3 | CHS3_YEAST | CSD2 | Chitin synthase (CS) | DIT101 | KIT2
Type:
Protein
Mol. Mass.:
131602.23
Organism:
Saccharomyces cerevisiae (Yeast)
Description:
P29465
Residue:
1165
Sequence:
MTGLNGDDPDDYYLNLNQDEESLLRSRHSVGSGAPHRQGSLVRPERSRLNNPDNPHFYYAQKTQEQMNHLDVLPSSTGVNPNATRRSGSLRSKGSVRSKFSGRETDSYLLQDMNTTDKKASVKISDEGVAEDEFDKDGDVDNFEESSTQPINKSIKPLRKETNDTLSFWQMYCYFITFWAPAPILAFCGMPKKERQMAWREKVALISVILYIGAIVAFLTFGFTKTVCSSSKLRLKNNEVSTEFVVINGKAYELDTSSRSGIQDVEVDSDTLYGPWSDAGKDASFLFQNVNGNCHNLITPKSNSSIPHDDDNNLAWYFPCKLKNQDGSSKPNFTVENYAGWNCHTSKEDRDAFYGLKSKADVYFTWDGIKNSSRNLIVYNGDVLDLDLLDWLEKDDVDYPVVFDDLKTSNLQGYDLSLVLSNGHERKIARCLSEIIKVGEVDSKTVGCIASDVVLYVSLVFILSVVIIKFIIACYFRWTVARKQGAYIVDNKTMDKHTNDIEDWSNNIQTKAPLKEVDPHLRPKKYSKKSLGHKRASTFDLLKKHSSKMFQFNESVIDLDTSMSSSLQSSGSYRGMTTMTTQNAWKLSNENKAVHSRNPSTLLPTSSMFWNKATSSPVPGSSLIQSLDSTIIHPDIVQQPPLDFMPYGFPLIHTICFVTCYSEDEEGLRTTLDSLSTTDYPNSHKLLMVVCDGLIKGSGNDKTTPEIALGMMDDFVTPPDEVKPYSYVAVASGSKRHNMAKIYAGFYKYDDSTIPPENQQRVPIITIVKCGTPAEQGAAKPGNRGKRDSQIILMSFLEKITFDERMTQLEFQLLKNIWQITGLMADFYETVLMVDADTKVFPDALTHMVAEMVKDPLIMGLCGETKIANKAQSWVTAIQVFEYYISHHQAKAFESVFGSVTCLPGCFSMYRIKSPKGSDGYWVPVLANPDIVERYSDNVTNTLHKKNLLLLGEDRFLSSLMLKTFPKRKQVFVPKAACKTIAPDKFKVLLSQRRRWINSTVHNLFELVLIRDLCGTFCFSMQFVIGIELIGTMVLPLAICFTIYVIIFAIVSKPTPVITLVLLAIILGLPGLIVVITATRWSYLWWMCVYICALPIWNFVLPSYAYWKFDDFSWGDTRTIAGGNKKAQDENEGEFDHSKIKMRTWREFEREDILNRKEESDSFVA
  
Inhibitor
Name:
BDBM49759
Synonyms:
(E)-3-(2,4-dimethoxyphenyl)-1-phenyl-2-propen-1-one | (E)-3-(2,4-dimethoxyphenyl)-1-phenyl-prop-2-en-1-one | (E)-3-(2,4-dimethoxyphenyl)-1-phenylprop-2-en-1-one | MLS000680272 | SMR000268417 | cid_5706277
Type:
Small organic molecule
Emp. Form.:
C17H16O3
Mol. Mass.:
268.3071
SMILES:
COc1ccc(\C=C\C(=O)c2ccccc2)c(OC)c1
Structure:
Search PDB for entries with ligand similarity: