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Target
RNA-directed RNA polymerase
Ligand
BDBM50191539
Substrate
n/a
Meas. Tech.
ChEMBL_932863 (CHEMBL3074361)
IC50
31200000±n/a nM
Citation
  TBA Med Chem Res 22:1866-1883 (2013)    Article 
Target
Name:
RNA-directed RNA polymerase
Synonyms:
2.7.7.48 | NS5B | RNA-directed RNA polymerase
Type:
PROTEIN
Mol. Mass.:
13231.83
Organism:
Hepatitis C virus genotype 1
Description:
ChEMBL_106647
Residue:
121
Sequence:
RCFDSTVTENDIRVEESIYQCCDLDPQARVAIKSLTERLYVGGPFTNSRGENCGYRRCRASGVLTTRCGNTLTCYMKAQAACRAARLRDCTMLVSGDDLVVICESAGAQEDAASLRAFTEA
  
Inhibitor
Name:
BDBM50191539
Synonyms:
2-{4-[4'-chloro-4-(isobutyrylmethylamino)biphenyl-2-ylmethoxy]-2-fluorophenyl}-1-cyclohexyl-1H-benzimidazole-5-carboxylic acid | CHEMBL212363
Type:
Small organic molecule
Emp. Form.:
C38H37ClFN3O4
Mol. Mass.:
654.169
SMILES:
CC(C)C(=O)N(C)c1ccc(c(COc2ccc(-c3nc4cc(ccc4n3C3CCCCC3)C(O)=O)c(F)c2)c1)-c1ccc(Cl)cc1
Structure:
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